Laboratory tests for C3 glomerulopathy and its application
QIN Wei-song
Abstract:C3 glomerulopathy is mainly caused by the dysregulation of alternative complement pathway,which results in the over activation of this pathway and subsequent glomerular injuries.Laboratory detections will be very helpful for the precise diagnosis of C3 glomerulopathy.Current available tests include functional complement assays,screening for autoantibodies against complement components,quantitation of complement components and regulatory proteins,and tests for genetic mutations or deficiencies in complement proteins.
Keywords:C3 glomerulopathyalternative complement pathwaylaboratory tests
Publication Date:2017-01-01
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:4( 786-789 )
Chinese Journal of Practical Internal Medicine

Chinese Journal of Practical Internal Medicine

PKUISTIC
ISSN:1005-2194
Year, Vol.(Issue):2017,37(9)