Pay attention to the diagnosis and differential diagnosis of C3 glomerulopathy
ZHANG Li-hua
LIU Zhi-hong
Abstract：C3 glomerulopathy is a recently introduced disease,and has drawn attention of renal pathologists and nephrologists.The characteristic histological feature is the presence of dominant C3 staining in the glomerulus by immunofluorescence staining.Abnormal activation of complement alternative pathway caused by congenital or acquired complement regulation deficiency is the main pathogenesis of C3 glomerulopathy.Timely and precise diagnosis to treatment decisions and improvement of disease outcome in patients with C3 glomerulopathy.The authors will focus on the pathogenesis and diagnosis of the disease in this review,hoping to improve the level of diagnosis and treatment.
Keywords：C3 glomerulopathydense deposit diseaseC3 glomerulog nephritiscomplement alternative pathway
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 777-780 )