Analysis of correlated factors of heart rate variability in patients with AMI undergoing primary PCI
TIAN Wen
YU Xiao-qing
Abstract：Objective To analyze the relationship between the markers of inflammation and heart rate variability (HRV) in patients with acute myocardial infarction (AMI) undergoing primary percutaneous coronary intervention (PPCI).Methods Forty-one patients with AMI undergoing PPCI were enrolled.Blood samples were collected for measurement of the white blood cell count (WBC),serum concentration of high sensitive-C reactive protein (hs-CRP),CK-MB and troponin Ⅰ (TnⅠ) during the first 24 hour after AMI.The information of heart rate variability (HRV) was collected by 24-honr ambulatory electrocardiogram.Results Compared to the patients with normal WBC,the concentration of CK-MB and TnⅠ was significantly higher in the patients with high WBC count,while the SDNN was decreased.In addition,a positive correlation was found between the WBC counts and serum TnⅠ concentration (r=0.319,P=0.042),and the WBC count was negatively correlated with SDNN (r=-0.404,P=0.009);serum hs-CRP level was negative correlated with SDNN(r=-0.325,P=0.038)and HF(r=-0.321,P=0.041).Conclusions In the patients with AMI after PPCI,the elevated WBC count is positively related to increased area of myocardial infarction.The WBC count and hs-CRP are negatively correlated with the HRV.
Keywords：acute myocardial infarctionprimary percutaneous coronary interventionwhite blood cellhigh sensitivity-C reactive proteinheart rate variability
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 560-563 )