Clinical manifestation, diagnosis and treatment of neurologic impairment of Sj(o)gren's syndrome
YANG Ping-ting
XU Feng
XIAO Wei-guo
Abstract：Sj(o)gren's Syndrome (SS) is an autoimmune disease characterized by sicca symptoms,anti-SS-A (Ro) or anti-SS-B (La) autoantibodies.Increasing evidence indicates that nervous system is involved in 20％ patients with SS.Nervous impairments include peripheral neuropathies and central neuropathies.Peripheral neuropathies associated with SS include sensory ataxic neuropathy,paintful sensory neuropathy without sensory ataxia,ganglionopathies,multiple mononeuropathy,cranial neuropathy,trigeminal neuropathy,autonomic neuropathy,and radiculoneuropathy.CNS disorders include headache,spinal cord involvement,neuromyelitis optica,seizures,motor and sensory deficit,movement disorders,and aseptic meningitis.To date,corticosteroids and other immunosuppresjsive agents remain to be the primary treatment in the neuropathy associated with SS.
Keywords：Sj(o)gren's syndromeperipheral nervous systemcentral nervous system
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 503-505 )