Pulmonary involvement in Sj(o)gren's syndrome
LI Xia
FEI Yun-yun
ZHANG Xuan
Abstract：Extraglandular organ systems of Sj(o)gren's syndrome (SS)may frequently be involved,including the respiratory system.Pulmonary involvement is defined by respiratory symptoms,pulmonary function or radiographic abnormalities.Clinical manifestations vary.Bronchiolitis and bronchiectasis are the most common airway manifestations.Interstitial lung disease is the most common lung disease of SS.Patients with SS are at high risk of lung lymphoma.Other lung abnormalities include pulmonary artery hypertension (PAH),pulmonary cystic lesions,amyloidosis,and pleural disease.Corticosteroids alone or in combination with other immunosuppressors are quite necessary for the patients with progressive chest symptoms.PAH targeted therapy is recommended in SS-PAH patients.
Keywords：Sj(o)gren syndromeairway diseaseinterstitial lung diseasepulmonary artery hypertension
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 484-487 )