Clinical study of IMA combined with two-dimensional speckle tracking imaging for early diagnosis of unstable angina pectoris

ZHANG Nan; SUN Meng; WANG Cai-xia; WANG Rui-hua; ZHAO Zhi-qiang; GAO Jia; WANG Rui

doi:10.19538/j.nk2017040115

Abstract：Objective To explore the clinical significance of combined application of IMA with two-dimensional speckle tracking imaging (2D-STI) in the early diagnosis of unstable angina pectoris.Methods According to the results of coronary angiography,118 patients,who had single lesion of left anterior descending artery,stenosis greater than 70％ and were treated with PCI,were selected as the experimental group;78 patients who had not coronary artery stenosis were as the control group.Two groups were recorded chest pain symptoms and 12 lead ECG during operation,and were detected IMA and echocardiography in the preoperative and postoperative period respectively.Use 2D-STI technique to calculate the global peak longitudinal strain (GPLS).Statistical analysis was performed using SPSS 19.0 software.Results There was no difference on preoperative IMA or GPLS between group PCI and control group(P＞ 0.05).There was difference on preoperative IMA,GPLS group PCI and control group(P ＜ 0.05).In group PCI,preoperative and postoperative IMA and GPLS had significant difference (P ＜ 0.05).In control group,preoperative and postoperative IMA and GPLS had no difference (P ＞ 0.05).The sensitivity of IMA and GPLS (2D-STI) single detection of myocardial ischemia after percutaneous coronary intervention in group PCI were 85.22％ and 66.96％,and the specificity was 65.38％ and 74.36％.The sensitivity of IMA and GPLS (2D-STI) combined detection of myocardial ischemia after percutaneous coronary intervention in group PCI was 64.35％,and the specificity was 93.59％.The specificity of combined detection was significantly higher than that of the single detection,there being statistical difference (P ＜ 0.05).Conclusion IMA combined with 2D-STI is helpful for the early diagnosis of UA,which can provide reference for clinical UA diagnosis.