Analysis of prognosis of cardiac resynchronization therapy for patients with chronic heart failure with true or non-true complete left bundle branch block
LI Yang
ZHANG Lin
LI Jian
HOU Zhi-wen
YU Bo
Abstract：Objective To analyze retrospectively the clinical response and prognosis of cardiac resynchronization therapy (CRT) for patients with chronic heart failure (CHF) with true complete left bundle branch block or non-true complete left bundle branch block.Methods Tolally 47 patients were collected with implantation of CRT-P/D in the First hospital of China Medical University from Dec.2005 to Dec.2015.T-he 47patients were divided into 2 groups:true-complete left bundle branch block (t-LBBB) group,(n=25),non-true left bundle block (nt-LBBB) group,(n=22).The difference in clinical materials and outcomes was analyzed in 2 groups.Results The mean absolute increases in LVEF in t-LBBB group were more significant than those in nt-LBBB group [/△LVEF:t-LBBB vs.nt-LBBB:(17.12±6.80)％ vs.(11.29±9.91)％,P=0.039];the mean absolute reduction in LVEDD and LVESV in t-LBBB group was also more significant than that in nt-LBBB group[△LVEDD:t-LBBB vs nt-LBBB:(-9.88±6.55)mm vs (-5.77±6.57)mm,P=0.041],[LVESV:t-LBBB vs nt-LBBB (-54.56±37.14)mL vs (-25.59±46.81) mL,P=0.025].Multivariate analysis showed that t-LBBB was independent predictors of response to CRT.The non-LBBB group showed the worst clinical response and prognosis.Conclusion The patients with the t-LBBB morphology are related to a better response to CRT.
Keywords：cardiac resynchronization therapychronic heart failuretrue complete left bundlebranch block
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 334-338 )