Clinical characteristics of type 2 diabetes patients with high blood ketone under non-stressful conditions
JIANG Can
FENG Wen-huan
ZHU Da-long
BI Yan
SHEN Shan-mei
LI Ping
ZHANG Ning
Abstract：Objective To investigate the clinical characteristics of hospitalized patients of type 2 diabetes (T2DM) with high blood ketone under non-stressful Conditions.Methods Totally 134 T2DM patients whose random peripheral blood glucose was beyond 13.9mmol/1 were divided into high blood ketone group (n=25) or non-high blood ketone group (n=109) according to the value of peripheral blood ketone ≧ 0.6mmol/L or not when they were hospitalized.Gender,age,body mass index (BMI),waist circumference,HbAlc,fast blood glucose (FBG),serum C-peptide,biochemistry,thyroid function,bone metabolism index and antidiabetic drugs before admission were compared.Results Patients in high blood ketone group were younger,with shorter duration,higher serum HbAlc and fasting blood glucose (FBG) levels,lower serum postprandial C-peptide and free triiodothyronine (FT3) levels,and fewer types of antidiabetic drugs and lower insulin doses before admission.Younger age,shorter disease duration,higher HbAlc and lower FT3 serum levels were independent risk factors of higher blood ketone.Conclusion Hospitalized T2DM patients with ketosis under non-stressful conditions are not uncommon.Strengthening T2DM screening and strictly controlling glycemia in younger people might avoid severe hyperglycemia and ketosis.Peripheral blood ketone determination helps to diagnose ketosis and prevent the development of DKA.
Keywords：type 2 diabetes mellitusnon-stressful conditionblood ketoneclinical characteristics
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 326-329 )