Damege of masked hypertension on kidney in type 2 diabetes patients
ZHOU Jia-nan
DU Hong-yan
HE Hong-bo
YAN Zhen-cheng
ZHU Zhi-ming
NI Yin-xing
ZHONG Jian
Abstract：Objective To evaluate the impact of masked hypertension (MH) in type 2 diabetic patients on kidney damage.Methods Totally 131 hospitalized patients with type 2 diabetic mellitus (T2DM) who accepted 24-h ambulatory blood pressure monitoring (ABPM) were enrolled,divided into MH group (n=70) and normotensive (NT) group (n=61) according to ABPM results.All patients underwent 24-h urine protein quantity test,and relevant data were compared in MH and NT patients.Results The incidence of MH was identified in 53％ in hospitalized diabetic patients in the study.Masked hypertensive patients and normotensive patients were not different in terms of age,diabetic duration,fasting blood-glucose (FPG),glycosylated hemoglobin (HbA1c),lipid profiles,smoking status,drinking history and body fat rate.BMI of MH patients were significantly higher than those of NT group (24.72±3.12 vs 23.57±+2.86,P=0.031).The incidence of diabetic microalbuminuria (MAU) (24.3％ vs 4.9％,P=0.002) was also increased in masked hypertensive patients.Regression analysis indicated that 24h-mALB was related to daytime systolic blood pressure measured by ABPM and diabetic duration (P=0.021,0.024).Conclusion Type 2 diabetic patients with MH have increased risk in kidney microvascular complications.
Keywords：masked hypertensiontype 2 diabeteskidney damage
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 255-258 )