DOI: 10.7504/nk2015020403
Predictive value of red cell distribution width on short-term prognosis of chronic obstructive pulmonary disease
SONG Yu
YANG Yuan-hua
WANG Chen
Abstract：Objective To study the predictive value of red cell distribution width (RDW) on short-term prognosis of patients with chronic obstructive pulmonary disease (COPD).Methods A total of 543 hospitalized patients due to acute exacerbation of COPD (AECOPD) were recruited in the study.Research data were collected during the remission period.Six months follow-up was started after discharged,and the endpoints were acute exacerbation and death.Statistical methods were used to evaluate the predictive value of RDW for the short-term prognosis.Results Multivariate cox regression analysis showed that RDW was an independent risk factor for acute exacerbation (HR =1.129,95％CI 1.038-1.228,P =0.005) or death (HR =1.303,95％CI 1.123-1.513,P =0.001) after the AECOPD patients were discharged.After exclusion of patients with lung cancer and ischemic heart disease,RDW was still the risk factor for death (HR =1.24,95％CI 1.012-1.518,P =0.038).We calculated the cut-offvalue of RDW (13.6％) by receiver operating characteristic curve (ROC).Kaplan-Meier analysis showed that the prognosis of the RDW ≤ 13.6％ group was significantly better than the RDW ＞ 13.6％ group.Conclusion High levels of RDW significantly correlate with poor prognosis of COPD.RDW is an independent risk factor for acute exacerbation and death.
Keywords：chronic obstructive pulmonary diseasered cell distribution width
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)