DOI: 10.7504/nk2014050402
Comparative analysis of controlled attenuation parameters in evaluation of liver steatosis using FibroTouch and FibroScan(R)
ZHU Meng-fei
LIU Jing
WANG Jie
CHENG Gong-ying
LOU Guo-qing
SHI Jun-ping
Abstract：Objective To compare the controlled attenuation parameters (CAP) measurement of liver steatosis using FibroTouch and FibroScan?.Methods Patients with non-alcohol fatty liver disease (NAFLD) and chronic hepatitis B (CHB) were included from July to October 2013 and liver biopsy was completed on these patients.They were examined to collect the CAP values by FibroTouch and FibroScan-502 respectively.Results A total of 41 patients with CHB and 20 patients with NAFLD were recruited.CAP values of FibroScan and FibroTouch are positively correlated with BMI (r =0.42,0.61;P =0.02,0.000) and degree of liver steatosis (r =0.54,0.56;P =0.001,0.001).CAP values of 33 patients with ＞5％ fat degeneration of liver cells were significantly higher than those of patients with no fat degeneration (FibroTouch [252.18±41.23] dB/m vs [220.68 ±54.75] dB/m,P =0.04;FibroScan[291.61 ±56.80] B/m vs [215.75 ± 45.11] dB/m,P =0.000).CAP values of patients with liver steatosis ＜ 30％ were significantly lower than those of patients with liver steatosis ＞ 60％ by FibroScan ([258.73-± 52.54] dB/m vs [327.42 ± 49.08] dB/m,P =0.04).But there were no differences in CAP values among patients with liver steatosis less than 30％,between 30％-60％,and more than 60％.Conclusion CAP values by FibroTouch and FibroScan are positively correlated with body mass and degree of liver steatosis.CAP value is a good and noninvasive index to evaluate degree of liver steatosis.
Keywords：FibroTouchFibroScan?controlled attenuation parametersliver steatosisliver biopsy
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)