DOI: 10.7504/nk2014050303
Anticoagulation treatments related different types of vascular access on maintenance hemodialysis patients: a multicenter epidemiological investigation
Abstract：Objective To increase the understanding of vascular access in hemodialysis and to evaluate hemodialysis-related anticoagulation treatments and the associated hemorrhagic or thrombotic complications.Methods In this study,an epidemiological investigation was conducted in 1175 patients who underwent hemodialysis in seven blood purification centers in northern Chinese.The patients were divided into two groups based on the vascular access they used:arteriovenous fistula (AVF) group and central venous catheter (CVC) group.Results AVF was the most frequently used vascular access,and heparin was the most commonly used anticoagulant.Patients in CVC group experienced significantly greater rates of low molecular weight heparin (LMWH) administration,and had a higher rate in achieving thrombotic complications than those in AVF group.There were no significant differences in LMWH dosages in patients with thrombotic complications,as well as the proportion of patients who received antiplatelet drugs.Heparinized catheter lock solutions were excessively high in this study,which may lead to a risk of hemorrhage.Conclusion Hemodialysis-related anticoagulation treatments in China require additional improvements,especially for the patients using CVC as vascular access.There is an urgent need to develop clinical evaluation studies of anticoagulation treatments for achieving more standardized and targeted treatments.
Keywords：hemodialysisanticoagulantsvascular access
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)