Study on association of IL-10 592 and ESR1 T29C gene polymorphism with susceptibility to hepatitis B viras infection in Yi minority from Guizhou
SHAN Ke-ren
WANG Chan-juan
LONG Li
HE Yan
ZHANG Ting
LI Yi
TAN Kui
TU Qian
REN Xi-lin
GUAN Zhi-zhong
Abstract：Objective To investigate the association of IL-10 592 and ESR1 T29 C gene polymorphism with the susceptibility to hepatitis B virus in Yi minority of Guizhou.Methods Allelic frequencies of IL-10 592 and ESR1 T29 C were identified by PCR-RFLP.Results IL-10 592 polymorphism was associated with the susceptibility to HBV in Yi minority.There wasno association between ESR1 T29 C gene polymorphism and the susceptibility to hepatitis B virus in Yi minority.Conclusion IL-10 592 polymorphisms influence the susceptibility to HBV infection in Yi minority of Guizhou.The study suggests that IL-10 592 polymorphism may be a dangerous factor of HBV infection.
Keywords：Yi minority of GuizhouIL-10 geneESR1 gene
Publication Date：2010-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 334-336,后插1 )