Non-alcoholic fatty liver disease is associated with chronic kidney disease and diabetic retinopathy in type 2 diabetic patients
WU Jing-cheng
LI Xiao-hua
PENG Yong-de
Cheng Qun
Abstract：Objective To investigate the relationship of non-alcoholic fatty liver disease(NAFLD)with chronic kidney disease(CKD)and diabetic retinopathy(DR)in type 2 diabetic patients.Methods Prcvalences of CKD and DR were assessed in 448 type 2 diabetic patients,who were divided into two groups by the presence of NAFLD.Results(1)The prevalence of NAFLD was 59.4%in type 2 diabetic patients.(2)NAFLD patients had remarkably(P＜0.Oi)higher urinary albumin/creatinine ratio(UACR)and prevalences of CKD(30.8 vs 18.1%)and DR(35.7 vs 21.4%)than their counterparts without NAFLD.(3)Logistic regression analysis showed that NAFLD was associated with increased incidences of CKD(OR=1.9,P＜0.05)and DR(OR=2.8.P＜0.01)independent of age,sex,diabetes duration,BMI,hypertension,smoking,HbA1 C and serum lipids.Conclusion NAFLD is associated with increased prevalences of CKD and DR in type 2 diabetic patients.Early identification and intervention of NAFLD can help to prevent diabetic microvascular complications.
Keywords：type 2 diabetesnon-alcoholic fatty liver diseasechronic kidney diseasediabetic retinopathy
Publication Date：2010-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 41-43 )