Study on type 2 diabetes mellitus with subclinical hypothyroidism in Jiangsu

Abstract：Objective To explore the correlation between subclinical hypothyroidism and type 2 diabetes. Methods Dia-betic patients who had lived for at least five years and aged more than 20 yeasrs old were sampled from six layers in Jiang-su Province by a stratified cluster sampling technique, Serum was sampled from 416 subjects and serum thyroid function was measured by chemiluminesecence. Results (1 )The prevalence rate of subclinical hypothyroidism was 12. 21% ,the proportion of subclinical hypothyroidism was 52. 63% in all diabetic combined with thyroid disease, which was significant-ly higher than those of other thyroid diseases( P <0. 01). (2) Compared with euthyroid diabetic patients,subclinical hypo-thyroidism patients was much older,and the diabetes duration was significantly longer(P <0.01 ). 3. Serum FT_4 level in subclinical hypothyroidism group was significantly lower than that of euthyroid group in diabetes [( 16. 26 ±2. 51 )pmol/L vs (17. 56 ±2. 60) pmol/L, P < 0. 01 ]. Conclusion It is common that subclinical hypothyroidism combined with diabetes in diabetic patients in Jiangsu Province,which may be influenced by age and diabetes duration,and more attention should be paid to the follow-up and diagnosis of subclinical thyroid disease in diabetic patients.