Anticoagulants for patients with acute cerebral infarction
WANG Ting
WU Wei-ping
Abstract：A large metaanalysis showed that immediate anticoagulation of patients with acute ischemic stroke was not associated with a significant reduction in death or dependency. The heparin data from the International Stroke Trial(IST) suggest that the use of early unmonitored subcutaneous heparin willreduce early stroke recurrence risks, but these benefits can be eliminated by increased hemorrhagic complications. The use of lower doses of heparin may provide more benefits rather than hemorrhagic side effects. We recommend early anticoagulation for various specific stroke subgroups including cardioembolic stroke, progressing stroke, stroke due to large-artery atherosclerotic stenosis, documented intra-luminal thrombus,and deep venous thrombosis prophylaxis.
Keywords：acute cerebral infarctionanticoagulation
Publication Date：2009-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 991-993 )