The clinical application of adenosine triphosphate in radiofrequency ablation
Abstract：Objective The aim of this study is to investigate whetheradenosine triphosphate(ATP) has the optimal dose to identify accessory pathway for elevating the successful rate of radiofreqency ablation and declining the oblivious diagnostic incidence in multiple accessory pathway during application of radiofreqency ablation.Methods 37 patients without accessory pathway who had retrograde conduction in atrioventricular node and 45 patients with concealed accessory pathway were respectively given adenosine triphosphate in 0.2mg/kg，0.25mg/kg and 0.3mg/kg to assess the value of application of ATP in radiofrequency ablation through observing the effects of ATP on atrioventricular node and accessory pathway during pacing at right ventricle. Results ATP in dose of 0.25mg/kg had the sensitivity of 83.2%，the specificity of 97.78%，positive predictive value of 96.88%，negative predictive value of 88.00%，and accuracy of 91.46% for testing whether accessory pathway existed. Conclusions ATP in dose of 0.25mg/kg has an important significance to identify accessory pathway with retrograde conduction in atrioventricular node concurrently，it can not elevate the diagnostic value to increase the dose of ATP.
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Publication Date：2001-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 276-277 )