Research advances in the treatment methods of head and neck schwannomas
XU Yong
YU Wen-yuan
SHAO Yu
XU Jin
HU Shao-ting
LI Long-fei
CHEN Zheng-gang
Abstract：Head and neck schwannomas are relatively uncommon benign tumors that may present with both cystic and solid components,with the potential for malignant transformation in rare instances.These tumors often develop bilaterally along the nerve axis and,upon aspiration,typically yield a brownish,blood-tinged,non-coagulated fluid.Schwannomas in the head and neck region generally exhibit slow growth and are frequently associated with symptoms such as tender-ness,radiating pain,and other neurological manifestations.Head and neck schwannomas are generally resistant to con-ventional radiotherapy,with surgical excision being the most commonly employed treatment modality.However,surgical intervention is often complicated by adhesion to adjacent tissues,which can result in damage to the nerve of tumor origin.Additionally,the recurrence rate following surgery is extremely high.In recent years,significant advancements in thera-peutic approaches have led to notable progress in the management of head and neck schwannomas.This article reviews current treatment approaches,including traditional surgical resection,minimally invasive techniques,radiofrequency ab-lation,stereotactic radiosurgery,and targeted therapies,discusses current research hotspots and looks forward to future research directions.
Keywords：head and neck schwannomasminimally invasive techniquesradiofrequency ablationstereotactic radiation therapytargeted therapy
Publication Date：2025-09-30
Online Publishing Date：2025-10-30(First online date of this platform, not the publication date of the document)
Pages：9( 598-606 )