Research progress of gelatin methacryloyl hydrogel in periodontal disease treatment
GUO Shui-xiang
ZHANG Ge-ge
HU Jin-yue
WANG Li-na
Abstract：Periodontal disease is an inflammatory infectious disease with high prevalence that can lead to destruction of periodontal tissues.Topical periodontal therapeutic agents have always been a hotspot in its treatment.Gelatin methacry-loyl(GelMA)hydrogel,widely used in antimicrobial drug delivery and regeneration of bone,cartilage and other tissues due to its controllable physicochemical properties,good biocompatibility and degradability,can be used as an excellent periodontal topical slow-release agent.This paper reviews the research progress of GelMA hydrogel in recent years in in-hibiting periodontitis-causing bacteria and the progression of periodontal inflammation,and its role in promoting the re-generation of periodontal tissues,aiming to provide a reference for the clinical application of GelMA hydrogel in the treat-ment of periodontal diseases.
Keywords：gelatin methacryloyl hydrogelperiodontal diseaseantibacterialanti-inflammatorytissue regeneration
Publication Date：2025-02-27
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 99-103 )