Study on recurrence time and prognostic factors of recurrent tongue squamous cell carcinoma
HOU Cheng-su
YIN Yu-lan
ZHANG Yu-han
WANG Lei
ZHANG Ye
ZHANG Shi-jian
Abstract：Objective The risk factors related to recurrence time and prognosis of recurrent tongue squamous cell carci-noma(rTSCC)were analyzed.Methods A total of 177 rTSCC patients admitted to the Ninth People's Hospital Affiliat-ed to Shanghai Jiao Tong University School of Medicine and the Department of Oral and Maxillofacial-Head and Neck Oncology of Fengcheng Hospital,Fengxian District,Shanghai,from January 2012 to June 2017 were collected.Clinico-pathological data and survival information of the patients were collected.The factors related to recurrence time and prog-nosis of rTSCC patients were analyzed.Results Recur-rent lesions may involve the anatomical structures of the contralateral tongue,floor of the mouth,hyoid bone,man-dible,epiglottis,parapharynx,and tongue base.The recur-rence time of rTSCC patients was significantly correlated with gender and smoking history,and the differences were statistically significant(P＜0.05).Comparative analysis of the 3-year survival rate and 5-year survival rate of pa-tients showed that the T stage,surgical margin,N stage,clinical stage and histopathological grade of recurrent tu-mor were significantly correlated with the prognosis of re-current patients,and the above factors and the time of tu-mor recurrence all affected the overall survival of pa-tients,the difference being with statistical significance(P＜0.05).Conclusion Clinicians should focus on improving the analysis of staging,grading and other data of rTSCC patients,and advise patients to develop good living habits,in or-der to prolong the survival time of patients.
Keywords：tongue squamous cell carcinomarecurrenceprognosis
Publication Date：2023-12-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：7( 676-681,693 )