Application and research situation of toluidine blue in oral medicine
YAN Su-qin
ZHUANG De-shu
BI Liang-jia
Abstract：Toluidine blue (TB),an alkaline thiazide cationic dye,which can be combined with the acidic substances in the tissue cells,is an important dye for nucleic acid staining.Because of the specific binding of TB to nucleic acids,TB can be retained in cancer tissue preferentially and widely used in the diagnosis of malignant tumors of the mouth,the eye,and the upper digestive tract.TB plays an important role in medical research.In addition,as an effective photosensitizer,TB can be widely used in photodynamic antimicrobial and antitumor therapy.The purpose of this review is to provide a summary about the research situation and the application of TB in oral medicine.
Keywords：toluidine blueTBantimicrobialantitumorphotodynamic therapy
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 743-747 )