Effects of different concentrations of oxygen inhalation on pulmonary function and inflammatory factors in pediatric patients with maxillofacial surgery

CUI Hai-bin; ZHANG Qian

doi:10.19538/j.kq.2017.08.009

Abstract：Objective To investigate the effects of different concentrations of oxygen inhalation on pulmonary function and inflammatory factors in patients with maxillofacial surgery.Methods The 90 pediatric patients undergoing maxillofacial surgery in the Affiliated Stomatological Hospital of China Medical University from May 2015 to October 2016 were randomly divided into three groups,35％,50％,75％ FiO2 were inhaled.Preoperative,intraoperative and postoperative monitoring was performed on blood gas and lung function index;peripheral inflammatory factor changes were detected by ELISA.Results There was no significant difference in body weight,operation time,transfusion volume,blood loss or urine volume between the three groups (P ＞ 0.05).During mechanical ventilation,LA,pH and HCO3-levels were no significant difference among the three groups(P ＞ 0.05).Preoperative oxygen pressure is normal in the three groups,and oxygen partial pressure was statistically increased compared with preoperative group (P ＜ 0.05);postoperative oxygen partial pressure decreased,and compared with preoperative,the difference was statistically significant (P ＜ 0.05).The oxygen partial pressure of B group continued to rise,and the difference was statistically significant (P ＜ 0.05);the oxygen partial pressure of C group was increased in the operation,and the difference was statistically significant (P ＜ 0.05).In group A,the IL-1 beta was significantly decreased,and the IL-10 was increased,and compared with the preoperative phase there was significant difference (P ＜ 0.05).Conclusion Effects of inhalation of 35％ oxygen on pulmonary function and inflammatory factors are least significant in patients undergoing maxillofacial surgery.