Influence of Porphyromonas gingivalis and Treponema denticola in gingival crevicular fluid of patients with aggressive periodontitis on organic acid
SU Juan-juan
XUE Peng
Abstract：Objective To investigate the influence of Porphyromonas gingivalis (Pg) and Treponema denticola (Td) in gingival crevicular fluid (GCF) of patients with aggressive periodantitis (AgP) on organic acid.Methods Forty cases of AgP and 40 healthy volunteers in our hospital were selected and GCF was collected.GCF in booth of same quadrant of patients was collected,and plaque index (PLI),sampling location,probing depth (PD),sulcus beeding index (SBI) and attachment loss (AL) were recorded.CE was used to detect the concentration of organic acid;PCR was used to detect Pg and Td.The gray value of amplification entry stripe,which was detected positive,was given quantitative analysis;amplification target bars and brightness ratio showed the relative volune of target gene,which was PCR product quantity.Resuits PLI,PD,AL,concentration of acid,Pg/Td detection rate and Pg/Td product quantity of AgP group were higher than those of healthy group (P ＜ 0.05);Pg butyric acid concentration at positive detection point of AgP group was higher than that at negative detection point (P ＜ 0.05);organic acid concentration at Td positive detection point was higher than that at negative group(P ＜ 0.05).Conclusion Organic acid concentration in GCF of AgP patients shows product quantity of Pg and Td,which plays a certain guiding role in organic acid concentration of AgP.
Keywords：aggressive periodontitisAgPPorphyromonas gingivalisPgTreponema denticolaTdorganic acid
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 291-293,297 )