Research advance of impact of zinc on apoptosis and the osseointegration on the surface of pure titanium implants
WANG Pin-ying
HE Jing
ZHAO Bao-hong
Abstract：Zinc is a necessary trace element for organism,which important to the physiological regulation of organs and tissues.Zinc has an important biological effect in the process of apoptosis;it can inhibit apoptosis and induce apoptosis,both depending on intracellular concentration of zinc.The mechanism of zinc in influencing apoptosis is complex,which is the result of joint action of a variety of factors.Appropriate concentration of zinc coating on the surface of dental implants,which are made of pure titanium,modified by micro-arc oxidation,can promote the proliferation and differentiation of osteoblasts and the formation of bone matrix;also,different concentrations of zinc can affect the apoptosis of osteoblastic cells,probably through a mitochondria-mediated pathway.
Keywords：zincapoptosisdental implantosteoblast
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 180-185 )