The study of alveolar bone height changes in experimental type 1 diabetic rats
SUN Shang-min
YAN Lu
PAN Ya-ping
LIN Li
PAN Chun-ling
TANG Xiao-lin
Abstract：Objective To explore the alveolar bone height changes in experimental type 1 diabetic rats.Methods Twelve male Sprague-Dawley (SD) rats were randomly divided into experimental and control groups.The rats in the experimental groups were made type 1 diabetes mellitus (DM) by intraperitoneal injection of streptozotocin (STZ) (60mg/kg),while the control groups were injected with equal volume citrate buffer.All animals were sacrificed after 8 weeks.The alveolar bone loss (ABL) of the first molar,second molar and the third molar were measured from alveolar crest to enamel-cementum junction by stereoscope loupe.Results The rats in the control groups had no obvious bone damage;while experimental groups showed obvious bone destruction horizontally,there was significant difference statistically (P ＜ 0.05).Conclusion The alveolar bone damage was shown in rats with type 1 diabetes mellitus,and was horizontal absorption slowly.
Keywords：diabetes mellitusDMalveolarstreptozotocinSTZ
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 171-174 )