Cytotoxicity experiment in vitro of two kinds of self-made nickel-chromium ceramic alloy containing titanium
KANG Xiao-Yan
ZHAN De-song
Abstract：Objective To test the cytotoxicity of two kinds of self-made nickel-chromium ceramic alloy containing tita-nium. Methods From May 2009 to Dec. 2009 in the Centric Lab. of China Medical University the test was performed. After mixing the maceration extraction of the materials with the cultures of L-929 cells,we evaluated cytotoxicity by us-ing tetrazolium-based colorimetric assay. Results The cytotoxicity of the two kinds of self-made nickel-chromium ce-ramic alloy was stronger than that of pure Ti,and weaker than that of Ni-Cr alloy. Conclusion The self-made nick-el-chromium ceramic alloy containing titanium meet the clinical requirement and has better biocompatibility than the currently clinically commonly used alloy.
Keywords：nickel-chromium ceramic alloycytotoxicityMTT-assay
Publication Date：2013-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 682-684 )