Application of plasma exchange and hemodialysis in thrombotic microangiopathy during pregnancy
PENG Fang
WANG Yi-chun
Abstract：Thrombotic microangiopathy(TMA)during preg-nancy comprises a group of life-threatening disorders af-fecting both mothers and infants,characterized by complex pathogenesis,diverse clinical manifestations,and signifi-cant therapeutic challenges.Plasma exchange and hemodi-alysis are two important blood purification techniques that play a vital role in the management of pregnancy-associat-ed TMA.This article,based on the latest domestic and in-ternational research advancements and clinical experi-ence,provides an in-depth exploration of the application of plasma exchange and hemodialysis in pregnancy-associ-ated TMA.It analyzes therapeutic mechanisms,operational key points,efficacy evaluation,and complication manage-ment for different TMA subtypes,aiming to provide clinical physicians with references,optimize treatment strategies and improve maternal and fetal outcomes.
Keywords：pregnancythrombotic microangiopathyhemodialysisplasma exchange
Publication Date：2025-09-02
Online Publishing Date：2025-10-20(First online date of this platform, not the publication date of the document)
Pages：4( 901-904 )