Diagnosis and treatment of fulminant HELLP syndrome
SHEN Jian
WANG Zhi-jian
Abstract：HELLP syndrome(hemolysis,elevated liver enzymes,and thrombocytopenia syndrome)is a severe pregnancy-related complication characterized by high maternal and fetal mortality rates.Fulminant HELLP syndrome,a critical subtype of HELLP syndrome,is marked by rapid disease progression,significantly abnormal laboratory indices(e.g.,AST＞2000 U/L or LDH＞3000 U/L),and multi-organ dysfunction.This article reviews the pathophysiological mechanisms,clinical manifestations,diagnostic criteria,and therapeutic principles of fulminant HELLP syndrome.
Keywords：HELLP syndromefulminantpregnancy complicationsmultidisciplinary management
Publication Date：2025-09-02
Online Publishing Date：2025-10-20(First online date of this platform, not the publication date of the document)
Pages：4( 869-872 )