Prevention and management of perinatal venous thromboembolism
LI Dong-yan
WEI Yu-mei
Abstract：Venous thromboembolism(VTE)has become one of the leading causes of maternal mortality in China.With the increase in advanced pregnancy,obesity,and pregnancy complications,the incidence of VTE shows a trend of significant increase.Clinical manifestations of VTE are diverse but non-specific,with DVT typically presenting as unilateral lower limb edema and pain,while PE may present with dyspnea and chest pain.The diagnosis requires multiple auxiliary examinations including CUS and CTPA,with careful differentiation from conditions such as amniotic fluid embolism.The treatment primarily involves anticoagulation with low molecular weight heparin,while in severe PE cases thrombolytic therapy may be considered.High-risk populations should receive physical prophylaxis and necessary pharmacological prevention from early pregnancy.Early recognition and timely and standardized multidisciplinary treatment are crucial for improving maternal and fetal outcomes.
Keywords：perinatal pulmonary embolismdeep vein thrombosisanticoagulant therapyeducationprevention
Publication Date：2025-06-02
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 614-618 )