Risk factors for different degrees of intrauterine acidosis in full-term infants with brain injury
ZHOU Cui-xiang
SHI Wei
ZHAN Yue-wei
GUO Xiao-hui
Abstract：Objective To explore the risk factors for different degrees of intrauterine acidosis in full-term infants with brain injury.Methods A case-control study was conducted to collect a total of 463 full-term infants with brain injury who were born at the Obstetrics Department of Shenzhen People's Hospital from January 1,2016 to December 31,2021.A total of 219 full-term brain injury infants with intrauterine acidosis were selected as the case group,and 244 full-term brain injury infants without intrauterine acidosis were selected as the control group.According to the pH value,the case group was subdivided into a mild acidosis group(7.0≤pH＜7.2)and a severe acidosis group(pH＜7.0),and was compared with the control group.Binary logistic regression was used to analyze risk factors.Results Mode of delivery,abnormal electronic fetal monitoring,and placental abruption were risk factors for intrauterine acidosis in full-term infants with brain injury(P＜0.05).The OR value of abnormal electronic fetal monitoring in the severe acidosis group(3.854)was higher than that in the mild acidosis group(2.503).Placental abruption was a risk factor for severe acidosis(OR=20.691).Conclusion Full-term newborns with brain injury who also have placental abruption and abnormal electronic fetal monitoring are more likely to develop severe intrauterine acidosis,necessitating close clinical attention.
Keywords：brain injuryinfantsacidosisplacental abruptionelectronic fetal monitoring
Publication Date：2025-05-02
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 565-568 )