Metabolic changes and hyperglycemia in pregnancy
CHENG Yan
GU Wei-rong
Abstract：During pregnancy,a series of adaptive metabolic changes occur in the mother to meet the needs of fetal growth and development,mainly manifested as physiological insulin resistance.When various pathological factors cause an exacerbation of maternal insulin resistance or insufficient insulin secretion,it can lead to the occurrence of GDM in pregnant women with no previous history of diabetes,and also aggravate the abnormal glucose metabolism in pregnant women with pre-existing diabetes.In addition,hyperglycemia during pregnancy can also exacerbate the abnormal metabolic changes in the mother.This article will explore the impact of metabolic changes during pregnancy on hyperglycemia in pregnancy,helping readers understand the mechanisms of hyperglycemia in pregnancy from the perspectives of pregnancy physiology and pathology,and guiding clinical practice.
Keywords：pregnancyhyperglycemia in pregnancyinsulin resistance
Publication Date：2025-04-02
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 392-396 )