Subclinical chorioamnionitis and clinical out-come
SHENG Chao
WANG Zhi-jian
Abstract：Subclinical chorioamnionitis(CAM),which is defined as inflammation of the chorionic membrane and/or amniotic membrane without any clinical signs of CAM.Subclinical CAM is more likely to develop to clinical CAM,or intrauterine infection.Ascending microbial invasion from the lower genital tract appears to be the most frequent pathway for intra-amniotic infection.The most frequent microorganisms found in the amniotic cavity are genital mycoplasmas.Multiple studies have already found that subclinical CAM was associated with preterm birth within 34 weeks of ges-tation,preterm premature rupture of membranes,as-ymptomatic short cervix,neontal sepsis,chronic lung disease,and cerebral palsy.Early identification and rapid diagnosis of subclinical CAM can accurately guide maternal and fetal infection monitoring and an-tibiotic to decrease perinatal complications.
Keywords：subclinical chorioamnionitispreterm birthpreterm premature rupture of membranesneontal sepsiscerebral palsy
Publication Date：2023-12-02
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 1189-1192 )