State and prevention strategy of mother-to-child transmission of hepatitis B
TANG Jie
ZHOU Yi-hua
Abstract：Prevention of mother-to-child transmission(MTCT)of hepatitis B virus(HBV)plays a critical role in the control of chronic HBV infection.The combined immunoprophylaxis in neonates of mothers with posi-tive hepatitis B surface antigen,plus antiviral therapy in the third trimester of pregnant women with high viral load(HBV DNA＞2×105U/mL)or positive hepatitis B e antigen,can reduce MTCT to lower than 0.2％.Strict implementation of these measures in the whole country is the key to the elimination of chronic hepatitis B.
Keywords：hepatitis Bmother-to-child transmis-sionimmunoprophylaxisantiviral agent
Publication Date：2023-12-02
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 1185-1188 )