Recognition of TORCH screening

LIAN Yan; WANG Xie-tong

doi:10.19538/j.fk2023120105

Abstract：TORCH is a group of perinatal infectious pathogens that cause congenital defects.Most of ma-ternal infections are asymptomatic,making it difficult to identify primary infections.At present,TORCH se-rological test is the preferred clinical detection method.The detection indexes include TORCH specific IgM antibody,IgG antibody and IgG antibody affinity.TORCH screening before pregnancy is recommended to determine the basic immune status of women pre-paring for pregnancy,which is helpful for TORCH screening decision-making and risk assessment during subsequent pregnancy.TORCH screening in pregnancy is still controversial.TORCH serological test during pregnancy is the main means to determine maternal infection,but it can not be used as the evidence of fetal infection in utero.The screening time of TORCH in pregnancy should be determined according to the characteristics of the virus being screened.Whether TORCH infection during pregnancy will lead to in-trauterine infection depends on the immune status of the pregnant woman,the type of infection,and the duration of infection.The specific results of ultrasound can provide clues for the detection of intrauterine in-fection and guide the invasive prenatal diagnosis,whether there is structural abnormality is very impor-tant for judging fetal prognosis in confirmed intra-uterine infection.PCR detection of amniotic fluid is often used in the diagnosis of fetal intrauterine infec-tion.At present,there is no effective treatment for TORCH intrauterine infected fetus.For TORCH in-fection,we need to standardize the detection process,correctly interpret the test results and provide evi-dence-based medical support for the Chinese popu-lation through clinical big data research.