Epidemic characteristics and prevention strate-gies of syphilis during pregnancy
LIANG Yi-heng
FAN Shang-rong
Abstract：The incidence of syphilis in pregnancy is on the rise globally.In China,with the implementation of the elimination programs,the incidence of congenital syphilis and perinatal mortality have decreased sig-nificantly.High-risk factors for syphilis infection during pregnancy include:multiple sexual partners,drug abuse,moderate educational level,and unem-ployment.It is recommended that all pregnant women be screened with a syphilis serology test at the first visit,with treponemal and non-treponemal tests mu-tually confirming the diagnosis.Three doses of peni-cillin G benzathine 2.4 million units for intramuscular injection one a week are recommended for pregnant women with positive treponema pallidum particle ag-glutination assay(TPPA).After birth,the blood of newborns born to syphilis-infected mothers is taken to screen for TPPA,toluidine red unheated serum test(TRUST)and treponema pallidum IgM antibodies,and penicillin G benzathine of 50 000 U/kg intramuscularly is administered for preventing syphilis infection.
Keywords：syphilis in pregnancycongenital syphi-lisepidemic characteristicstreatmentpreventionscreen
Publication Date：2023-12-02
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 1164-1167 )