Clinical application of rectal diclofenac sodium suppositories in non-invasive outpatient hysteroscopy
FAN Jia-ying
YANG Yan
LU Yan-ling
XIE Jing-ying
ZHANG Tian-song
ZHU Ya-li
LIU Zhi-hong
HUANG Yan-qing
Abstract：Objective To assess whether rectal administration of diclofenac sodium suppositories or vaginal administration of misoprostol reduces pain during non-invasive outpatient hysteroscopy.Methods Totally 196 outpatients were given diagnostic hysteroscopy from April to December in 2016 in Guangzhou Women and Children's Medical Center.They were divided into three groups.A total of 63 patients in group A were not given any drug treatment before the procedure.A total of 51 patients in group B received 200ug misoprostol vaginally 2 hours before the procedure.A total of 82 patients in group C received 100mg Diclofenac sodium suppository rectally 60 minutes before the procedure.Patients were asked to record the severity of pain,using a visual analog scale ranging from 0(painless) to 10 (very painful).Comparie hysteroscopy time,intraoperative adverse reactions,postoperative analgesic demand and the occurrence of heart and brain syndrome (PASS).Results There were no significant differences in procedural time among the three groups (7.61-± 2.23 min in group A,7.04± 2.95 min in group B,6.12-1.72 min in group C).In group C,there were no PASS cases and no adverse reaction happened,which were significantly less than group B.Seven cases showed severe pain (8.75％) in group C,which had significant differences compared to the group A and group B.Conclusion Preoperative administration of diclofenac sodium suppositories has the advantages of less pain,no anesthesia,low incidence of adverse reactions and good effect.
Keywords：diclofenac sodium suppositorymisoprostolnon-invasivehysteroscopy
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 959-962 )