Relationship between serum amyloid A and subclinical chorioamnionitis in preterm premature rupture of membrane
ZENG Wen-juan
HUANG Qi-tao
WANG Hai-zhen
CAI Dan-chun
GAO Yun-fei
Abstract：Objective To investigate the relationship between serum amyloid A and subclinical chorioamnionitis in preterm premature rupture of membrane.Methods Thirty women of premature rupture of membrane,30 women of preterm premature rupture of membrane,30 women of term normal pregnancy (control group)and 30 women of preterm normal pregnancy in Nanfang Hospital,Southern Medical University between February and September 2016 were retrospectively analyzed for serum amyloid A level and placenta pathology.Results (1) The value of serum amyloid A in preterm premature rupture of membrane group was significantly higher than that in premature rupture of membrane group and control group,P＜0.001.(2)The incidence of histological chorioamnionitis in premature rupture of membrane group and preterm premature rupture of membrane group were higher than that in control group,P＜0.05.(3)The subgroup with histological chorioamnionitis showed a significant increase in serum amyloid A compared with the subgroup without histological chorioamnionitis,P＜0.05.(4)Serum amyloid A levels at a cut-off of 17.55 mg/L showed the highest Youden index for predicting preterm premature rupture of membrane with histological chorioamnionitis.Conclusion Maternal serum amyloid A is closely related to preterm premature rupture of membrane and histological chorioamnionitis.
Keywords：serum amyloid Apremature rupture of membranehistological chorioamnionitis
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 414-417 )