Study on the association between pelvic abscess and the cryptic growth cell
SUN Hai-zhu
LIU Jing-jing
LU Li
WANG De-ying
CHEN Xiu-hui
ZHAO Ji-zi
QIU Xiao-hong
Abstract：Objective To study the antibiotic function of inducing the E.coli to Cryptic Growth Cells(CGC)and its correlation with pelvic abscess.Methods Establish the models of pelvic inflammatory disease(PID);Use the SD female rats as research subjects;inculate the E.coli on the mesosalpinx;observe the pathological changes of reproductive system;determine the acute exacerbation.Establish PID acute exacerbation models and divide them into 4 groups:one for control and the other 3 for experiment.Use 1/2 concentration antibiotics to induce the CGC to simulate denormalized treatment.Observe the pathological change and CGC.Results In the PID models,the pathological change and time had positive correlation.Among these models,the course of PID was divided into acute and chronic stage.The acute exacerbation was defined as the range between 7th to 17th days after modeling,but there was no suppuration during that time.CGC was found from the models which were injected 1/2 concentration of cephalosporins during the acute exacerbation.At the same time,lesions appeared suppuration and serious tissue damage.Conclusion CGC can be induced by nonstandard antibiotic treatment for PID,which may induce pelvic abscess.
Keywords：pelvic abscesscryptic growth cellE.coli
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 319-323 )