Approach of developmental mode of embryo and fetal kidney, adrenal and liver in the near period

LI Yi-yang; FU Yan; SUN Jian; TIAN Li-na; SONG Hua; DING Yan-liang; DENG Wei-guo

Abstract：Objective To investigate the developmental mode of embryo and fetal kidney, adrenal and Ever during the different developmental stages. Providing the reference to appraisal developmental state of fetal urinary system and liver, and predicting dysplasia. Methods To collect 167 embryo and fetus in different gestational weeks, 135 fetuses during 12 ～ 36 gestational weeks were measured and analyzed ,including three diamensions diameters and weight of kidney,adrenal and liver. 32 embryo and fetus during 4+2 ～ 12+6 gestational weeks were observed the growth of kidney by histological method. Results The weight of fetal kidney in 3 gestational months was 0.1 g, in 9 gestational months was 7.8g. Increase of renal volume and weight was harmonious. From 3 ～ 9 gestational months, the development of left and right adrenal of 3D diameters length and weight were equal. In earlier embryonic stage, the volume of adrenal was more than kidney, in 4 ～ 5 months, they became equivalency gradually, and then the volume of kidney was more than adrenal. The weight of fetal liver in 3 gestational months wa 1.6g,in 9 gestational months was 85.7g,it raised 53 times. In 40 gestational days metanephrogenic blastema appeared in embryon lumbosacral ground substance by histological method. In 50 gestational days developed to metanephros and 90 days renal glomerulus with clear appearance and complete structure can be observed. Conclusion During the whole embryo and fetal period, development and molding of kidney is persistent. In earlier fetal stage, the volume of adrenal was more than kidney. 5 ～ 9 gestational monthes is the faster growth phase of fetal liver.