Heterotopic pregnancy after in vitro fertilization and embryo transfer: clinical analysis of 6 cases
Abstract：Objective To investigate the incidence, risk factors and clinical characteristics and treatment methods of
heterotopic pregnancy(HP)after IVF- ET. Methods We retrospectively analysed the clinical data of 6 patients with
HP after IVF - ET. Results The rate of HP was 0.95 %. All patients were transferred more than 3 embryoes. 4 pa
tients had history of tubal or pelvic disease. Abdominal pain was the most frequent symptom, and hypovolumic shock a
long with abdominal tenderness occurred in 2 cases. Approximately half of the patients did not complain of vaginal bleed
ing. 2 of them were diagnosed by transvaginal ultrasonography detection. 3 patients without adnexal mass were diagnosed
in the surgical procedure. 1 patient was misdiagnosed as appendicitis. Salpingectomy was the most common treatment
used for removal of the EP, 2 patients of the complicated gestation produced live children. Conclusion IVF - ET ap
pears to predispose to HP, particularly after tubal or pelvic diseases and multiple embryoes transfer. Transvaginal ultra
sonography is the most sensitive method for diagnosis. But the diagnosis is so difficult that all cases are diagnosed only af
ter rupture. Close monitoring by B- ultrasound in the early weeks of pregnancy in assisted reproduction patient is impor
tant so that we can prevent the deleterious effects of delayed treatment of HP.
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Publication Date：2001-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 32-34 )