A case report of fatal rotavirus parenteral infection
FENG Lin
WU Zhi-yuan
TAO Jian-ping
DANG Run
CHEN Yan-hui
ZHENG Li-xuan
CHEN Jing-lun
LIANG Yu-feng
Abstract：The clinical data of a child with parenteral infection of rotavirus admitted to Guangzhou Women and Children's Medical Center,Guangzhou Medical University in January 2023 were retrospectively analyzed,and the characteristics of the disease and diagnosis and treatment experience were analyzed based on the literature.A 1-year-old male child had vomiting,changes in stool traits and fever at onset,and he rapidly presented with convulsions,consciousness disturbance and shock.Cranial CT suggested acute necrotizing encephalopathy.Stool specimens were tested and showed weakly positive for rotavirus.CSF and blood samples were subjected to metagenomic next-generation sequencing(mNGS)and rotavirus was detected,Rotavirus infection was detected by local histopathology(hematoxylin-eosin staining,HE)in several organs,suggesting that rotavirus could cause damage to various organs through viremia.We should be alert to parenteral infection after rotavirus infection.
Keywords：childrotavirusrotavirus parenteral infectiondeath
Publication Date：2025-10-06
Online Publishing Date：2025-11-24(First online date of this platform, not the publication date of the document)
Pages：5( 876-880 )