Central precocious puberty with vasculitis-related moyamoya syndrome:one case report
XIE Dan-dan
CHEN Qiu-li
MA Hua-mei
JIANG Bo
LI Yan-hong
ZHANG Jun
GUO Song
ZHENG Ru-jiang
CHEN Zhi-xin
Abstract：A 3-year-old and 1-month-old female child visited the Department of Pediatric Endocrinology of the First Affiliated Hospital of Sun Yat-sen University in November 2020 due to"breast development with accelerated growth for 1.5 years".After examination,she was diagnosed with central precocious puberty(CPP).After admission,pituitary magnetic resonance imaging(MRI),magnetic resonance angiography(MRA),magnetic resonance spectroscopy(MRS),diffusion-weighted imaging(DWI)+susceptibility weighted imaging(SWI)and other examinations were performed,and the diagnosis was vasculitis-related smoke syndrome.Due to poor control of bone age(BA)in the child after treatment with gonadotropin-releasing hormone analog(GnRHa),17-hydroxyprogesterone(170HP)was checked.The level of 170HP was elevated,and the adrenocorticotrophic hormone(ACTH)stimulation test was performed,which indicated the possibility of non-classical congenital adrenal hyperplasia(NCCAH).This case of CPP accompanied by vasculitis-associated smoke syndrome is rare,suggesting that vasculitis-associated smoke syndrome can also be a cause of CPP.
Keywords：central precocious pubertyvasculitis-related moyamoya syndromenon-classical congenital adrenal hyperplasia
Publication Date：2025-09-06
Online Publishing Date：2025-11-05(First online date of this platform, not the publication date of the document)
Pages：4( 788-791 )