Research progress in the treatment of pediatric invasive fungal infections
HAN Hui-ling
WANG Yi
Abstract：Invasive fungal infection(IFI)is a fungal infection that invades deep tissues and organs as well as the whole body.Premature infants,newborns,and children with severe primary diseases are at high risk of invasive fungal infections.In recent years,with the increasing number of children with IFI,the increasing difficulty of pediatric IFI diagnosis,and the emergence of fungal resistance,the mortality rate has increased significantly.Pediatric IFI patients have low immunity,high complexity of drug use,atypical infection symptoms,and difficulty in early diagnosis,which increase the difficulty of clinical diagnosis and treatment in children with IFI.This article reviews the challenges faced by pediatric IFI in the treatment and the research progress in new drugs and new diagnostic and therapeutic methods,which helps to increase the attention to pediatric IFI patients,thus providing a reference for the prevention of high-risk children,the early diagnosis and treatment of pediatric IFI children,and the research direction of new drugs and new methods.
Keywords：pediatric invasive fungal infectionchallengeresearch progress
Publication Date：2025-09-06
Online Publishing Date：2025-11-05(First online date of this platform, not the publication date of the document)
Pages：6( 767-772 )