Study on the relationship between obstructive sleep apnea and allergic rhinitis in children
PU Jian
WANG Qian
LU Ying-xia
CHANG Li
WANG Rui-kun
HUANG Gui-min
LI Meng-yao
LIANG Jie-qiong
GU Qing-long
Abstract：Objective To investigate the relationship between obstructive sleep apnea(OSA)and allergic rhinitis(AR)in children,and to analyze the associated factors.Methods A retrospective analysis was conducted on the polysomnography(PSG)data,sleep questionnaire responses,and clinical records of 1,236 pediatric patients who underwent PSG at the Sleep Medicine Centre of the Children's Hospital affiliated to the Capital Institute of Pediatrics from January 2020 to May 2023.Patients included in the study had an apnea-hypopnea index(AHI)≥ 1 and complete questionnaires.Exclusion criteria comprised a history of asthma,neurological and muscular diseases,craniofacial anomalies,and previous adenoid tonsillectomy.Ultimately,1,137 patients with OSA aged 0-17 years were included.These patients were categorized into mild,moderate,and severe OSA groups based on their condition,and were further divided into AR and no-AR groups according to questionnaire and clinical information.The basic characteristics and PSG data of the two groups were compared,and Logistic regression was used to analyze the risk factors for OSA aggravation,R software(version 4.2.3)employed for statistical analysis.Results Of the 1,137 OSA patients,686 were male and 451 were female,with 476(41.9％)diagnosed with AR.The mean age of the AR group was 5.46 years,and their BMI was 16.80,which were 5.77 years and 17.20 in the no-AR group;these differences were not statistically significant.The AR group had a mean minimum oxygen saturation of 0.89,which was higher than the 0.88 observed in the no-AR group(P＜0.05).Additionally,the microarousal index averaged 0.85 events/h in the AR group,lower than the 1.01 events/h in the no-AR group(P＜0.05).No significant differences were found in the distribution of AR and no-AR groups across different OSA severity levels,and there was no significant correlation between moderate to severe OSA and the presence of AR.Conclusion The prevalence of AR is notably high among pediatric OSA patients.Furthermore,PSG parameters,specifically minimum oxygen saturation and microarousal index,are more favorable in patients with AR compared to those without AR.
Keywords：childobstructive sleep apneaallergic rhinitispolysomnography
Publication Date：2025-09-06
Online Publishing Date：2025-11-05(First online date of this platform, not the publication date of the document)
Pages：6( 756-761 )