Classification diagnosis and treatment management of systemic juvenile idiopathic arthritis
LUO Xi-wen
TANG Xue-mei
Abstract：Systemic juvenile idiopathic arthritis(sJIA)has a unique disease background and clinical profile,with various extra-articular manifestations and disease patterns.Its etiology remains unclear.The interaction between genetic and environmental factors contributes to the onset and progression of the disease.Inflammation control and targeted therapies are key to achieving disease remission.This review outlines the pathogenesis of sJIA,classification criteria,current research advances in diagnosis and treatment,and the main global principles for targeted therapeutic management,highlighting the importance of early diagnosis,precise intervention,and long-term follow-up in improving patient outcomes and quality of life,which helps to deepen clinicians' overall understanding of sJIA.
Keywords：systemic juvenile idiopathic arthritismechanismclassification diagnosistargeted therapy
Publication Date：2025-09-06
Online Publishing Date：2025-11-05(First online date of this platform, not the publication date of the document)
Pages：7( 728-734 )