Clinical analysis of 5 child patients with autoimmune pancreatitis
YU Xiao-zheng
WU Jie
Abstract：Objective To explore the clinical characteristics and outcomes of autoimmune pancreatitis(AIP)in children,and to provide ideas for clinical diagnosis and treatment.Methods Clinical data of 5 children diagnosed with AIP at Beijing Children's Hospital from July 2020 to January 2024 were retrospectively analyzed.The clinical symptoms,treatment methods and follow-up results were analyzed.Results Among the 5 children with AIP,there were 2 cases of type 2 AIP,2 cases were not specified and 1 case might be type 3 AIP.There were 4 boys and 1 girl,with an average age of(10.87±3.86)years.The main clinical manifestations were abdominal pain(4 cases)and jaundice(3 cases).All patients had normal serum IgG4 levels.All children had typical imaging manifestations,including focal pancreatic enlargement in 4 cases and diffuse pancreatic enlargement in 1 case,with 1 case also having a focal pancreatic mass.One child underwent a pathological biopsy,which showed periductal lymphocyte infiltration and interstitial inflammatory changes in the pancreas.All 5 children achieved clinical and imaging remission after hormone treatment.No recurrence was observed during follow-up.Conclusion The incidence of AIP in children is low,the clinical features are not obvious,and the hormone therapy has significant effect.A full understanding of the clinical features of AIP in children is helpful for early identification of AIP and avoiding missed diagnosis and misdiagnosis.
Keywords：autoimmune pancreatitischildclassificationhormone
Publication Date：2025-07-06
Online Publishing Date：2025-09-04(First online date of this platform, not the publication date of the document)
Pages：4( 582-585 )