Expert consensus on individualized dosing of tacrolimus for pediatric glomerular diseases
Division of Therapeutic Drug Monitoring,Chinese Pharmacological Society
Guangdong Pharmaceutical Association
Editorial Committee of Chinese Journal of Practical Pediatrics
CAI He-ping
CAO Juan
CHEN Xiao
CHEN Feng
CHEN Pan
CHEN Wen-qian
CHEN Ze-bin
FANG Xiao-yan
FAN Xiao-mei
GAO Xia
HUANG Chen-rong
HUANG Ling-fei
JIA Yun-tao
LI Jia-li
LI Yi-lei
LI Zhi-ling
LI Zhong
LI Xue-juan
LIN Yun-zhu
LV Meng
MA Kui-fen
MAO Jian-hua
MIU Jing
MO Xiao-lan
PENG Xiao-xia
SHEN Qian
WANG Xiao-ling
Abstract：Tacrolimus is a widely used immunosuppressant in the treatment of pediatric glomerular diseases.However,precision dosing presents a challenge due to significant individual differences in pharmacokinetics and pharmacodynamics.Currently,there are no guidelines for individualized dosing of tacrolimus in the treatment of pediatric glomerular diseases,either domestically or internationally.With the aim of assisting physicians and pharmacists in implementing individualized dosing and improving patient satisfaction,the consensus,summarizes the application of tacrolimus in pediatric glomerular diseases,its concentration monitoring,pharmacogenetic testing,and pharmaceutical care based on the latest research advancements and clinical practice experience both domestically and internationally.
Keywords：tacrolimuschildglomerular diseasesindividu-alized medicinepharmaceutical care
Publication Date：2025-01-05
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：12( 1-12 )