Comprehensive life-cycle management of male congenital hypogonadotropic hypogonadism
SU Wei
SU Zhe
Abstract：Congenital hypogonadotropic hypogonadism(CHH)is primarily characterized by manifestations such as micropenis,cryptorchidism,and partial or complete lack of development of secondary sexual characteristics.The disease has a complex pathogenesis and exhibits a wide range of clinical phenotypes.Treatment focus and protocols vary across different stages of life and clinical phenotypes.Timely diagnosis and appropriate treatment are beneficial to sexual development,bone and metabolic health,and may also help to mitigate some of the psychological impacts of CHH.
Keywords：congenitalhypogonadotropic hypogonadismhypothalamic-pituitary-gonadal axispulsatile gonadotropin-releasing hormone therapy(pulsatile GnRH therapy)recombinant human follicle-stimulating hormone
Publication Date：2024-11-06
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 820-825 )