Food protein-induced enterocolitis syndrome in children
WU Jie
CHEN Yun-yan
Abstract：Food protein-induced enterocolitis syndrome (FPIES) is a non-IgE mediated gastrointestinal allergic disorder,and the pathogenesis is still unknown.The clinical manifestations include repetitive severe vomiting and diarrhea.Acute FPIES can result in dehydration,lethargy and even shock.Chronic FPIES is mainly characterized by weight loss and growth retardation.FPIES mainly affects infants and toddlers.Common allergen includes milk,soybean,oats,fish and eggs.The diagnosis is based on typical clinical manifestations and the fact that avoiding possible food source can alleviate the symptoms.If necessary,oral food challenge (OFC) is required to confirm the diagnosis or to find out the food allergy sources.The key treatment measures are to avoid allergen food and to carry out symptomatic treatment during acute phase.
Keywords：enterocolitisfood proteinchild
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 746-750 )