Eosinophilic esophagitis in children
LI Dong-dan
XU Xi-wei
Abstract：Eosinophilic esophagitis is a relatively rare chronic immune-mediated esophageal disease,which is associated with allergic diseases,and currently its etiology and pathophysiology mechanism is not yet clear.Clinical manifestations are esophageal dysfunction,and symptoms vary with age.Histopathology is necessary for diagnosis,but clinical manifestations and proton pump inhibitor responses also need to be consided.The basis of treatment is dietary therapy and/or drug therapy;dietary therapy is a first-line treatment for children,which can effectively relieve the disease.Swallowing fluticasone or budesonide local hormone therapy is very effective,however,the data of long-term safety and efficacy are not enough.For esophageal stenosis of EOE children,if necessary,endoscopic treatment may be performed.For other therapeutic agents,such as biological agents and immunological preparations,further study is needed.
Keywords：eosinophilic esophagitischilddiagnosistreatment
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 739-743 )